OK, so lets start with the cam, its pretty simple. if lets say i have a cam with .3 lift and I decide i want a cam with say .9 lift and nothing else but the lift has changed then there is absolutely a chance that there will be no interference. it doesn't matter if the pistons are full flat top which was only used in 86 or if they have reliefs, you absolutely cannot give cam advice based on lift alone as lift while playing a part doesn't play a big enough part in itself to dictate p/v issues. A cam can be advanced or retarded 2* to change p/v clearance, a cam can be ground differently, the duration is a big player in cam fitment and selection and the total spec package is what is used to determine fitment issues.
As for pistons, just about every 289,302 and 351w has some kind of relief in the piston from the factory(86 year being the exception) be it 2 reliefs, 4 reliefs , reliefs with a dish or just a dish. We dont know what he has as theres always the exception to the rule but its more likely there are reliefs in his motor and if by chance there aren't, even in 86 we put cams in our motors so long as we watched the duration #'s there were no issues. When choosing any parts for a motor you cant look at the part as an individual, you have to have a working knowledge of the motor and how each part will work together with the rest of the platform, also knowing how different manufacturers rate or spec their product helps. one point to that is most companies base off of zero deck, I have yet to come across a stock motor that has zero deck and in fact its been more common to be .020-.030 in the hole which of course just adds more clearance for p/v. If thats the cam you want, buy it, when you are ready to upgrade your parts then you'll know. comp cams will take a cam back if its unopened years after you purchased it so you have time. If you cant wait then just look down a spark plug hole for reliefs.